The New E8000 series is going to be released in January 2008. Wait for them before you waste money on the 6850. The E8400 performed better and overclocks much higher.
The Core 2 Duo will be better at stockspeed. It can also be overclocked more than the Athlon 6400+ which is already clocked near it's limit.
The upcoming Penryn CPUs (E8xxx series) are expected to be released on January 20th. I don't know their tray prices (i.e. lots of 1,000), but expect to pay a premium of up to $100 during the initial 4 - 6 weeks due to expected overwhelming demand. When the E6600 was released in 2006, the expected street price was about $320, I remember seeing etailers selling them in excess of $400 for the first several weeks.
Some preliminary benchmarks showed that an E8xxx CPU outperforms a similarly clocked E6xxx CPU by 5% on average for games; (but not more than 7% for any specific game).
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