There are many options, it all depends on your budget for the recording side of things. for Guitar and MIC you'd need one 1/4" input and one XLR input, so the e-mu 0202 might be a good option, I got the 0404 myself, more input options.
Here are some USB 2.0 options from m-audio, creative/e-mu:http://www.m-audio.com/index.php?do=products.family&ID=USBinterfaces
this is the one I got to replace my creative audigy 2zs platinum:http://www.emu.com/products/product.asp?category=610&subcategory=611&product=15186
there are also a bunch of PCI/internal options too, which come with frontpanels to plug into.
if budget isn't an issue, maybe look for a firewire 800 interface, with onboard DSP or something?