Hi again.
1) 3Gbps is 3 gigabits, not gigabytes. To see how many bytes, you take 3 gigabits, which is also 3000 megabits and divide by 8. There are 8 bits in 1 byte. My explanation of the speed of my 3ware Raid 5 was meant to show the performance impact that Raid 5 has. If I were to take those same 4 drives and run them in Raid 0 which stripes data across all 4 drives, then the read and write speed should average 320 MB/s. The average speed of each drive is 80MB/s, so that is why he Raid 0 speed is 4x80=320. However, Raid 5 is different. Frist off, Raid 5 loses 1 drive due to parity storage. So, with 4 500GB drives, you lose 1 and have 3-500GB. Those 3 drives average 90MB/s, so 90x3=270 MB/s max Read speed but writes are different. With Raid 5 writes, due to the way it works, there is a write speed penalty which greatly depends on the Raid controller. With a good controller, that 270MB/s max speed only incurs a slight speed penalty down to 200-230MB/s. I hope I didn't confuse you anymore.
The Highpoint 4320 8 port SAS/SATA Raid controller is on sale at newegg for $390.
http://www.newegg.com/Product/Product.aspx?Item=N82E16816115056
This card is the best card at this price by far. I would trade my 3ware 8port card for this even though I paid $600 for mine. This Highpoint has Intel's IOP348 processor which is what is used to calculate parity in Raid 5, and the IOP348 is one of the best on the market. Also, the card is PCI-Express "x8" so the PCI-Ex bus shouldn't be a limiting factor. Don't worry that its SAS & SATA, that just means if you want to upgrade to SAS drives some day, you can.
I would highly suggest getting 2 of these cards because of the great sale price and keep one as a spare.
For your drive setup:
1) OS + Page File on a 2 drive Raid 1. This is the standard in servers.
2) 4-6 1.5TB or 2TB drives in Raid 5 for Database.
3) 2 - 250GB drives in Raid 1 for daily backup
Both Raid 5 and Raid 1 can be on the same Raid controller. However, if the time it takes to backup needs to be as quick as possible, then using another controller for the Backup drives is needed. What about the onboard Raid that comes on the motherboard? If the motherboard is Intel-based, then it should already have a decent Raid controller built in. Using this controller, you can create your Raid 1 for OS and also a Raid 1 or even Raid 10 for the backup drives. This right here will help with speeds quite a bit.
I figured your database would be very large due to the amount of daily backup so that is why I chose 1.5-2 TB drives.
Another extremely important reason to use separate controllers is the database will grow and you will need to add more drives down the road. Also, you should get 1 extra drive for the Raid 5 to use as a hot-spare that can be used to rebuild in case of a drive failure.
I would get a good UPS also as that will help keep your entire system up.
If you need an entire system built, many of us here would put together the parts list for you.