Folding is running a lot of simulations, but the real problem is going through the live patient trials and separating the stuff that works from the stuff that gives a placebo effect. Over 90% of what is tried doesn't make it through live trials for one reason or another. I took some liver damage myself a couple years back from a new drug. The best I know, some, possibly most, of the Folding concentrates on DNA analysis and trying to separate the exact genes involved in MS, verses random defects. One of the things that has been found is that there are a number of subtypes of MS, which is impeding a specific vacination. Things are far better now than they were 30 years ago, and I think that Folding has been helping a lot. If nothing else, it helps keep us from persueing wrong leads.