If you can clone again, that will be the simplest solution. I presume you will want to put the new clone on the 250 GB drive and NOT save anything that is on that drive now. And you want to make the clone use the full 250 GB as one volume.
I have not used Ghost, but look for things like this:
1. Is this your boot drive? If yes, you will need to check that the software is set to make the Destination drive bootable. If not, do NOT make it bootable.
2. As above, look for where you specify the Destination drive size, and set it to the max available.
3. If the choice is offered, set for NTFS File System - not FAT32.
4. To use a drive over 130 GB as one volume, you must have what's called "48-bit LBA Support" in the hardware (you have this because ALL SATA drives and controllers have it) and in your OS. VISTA has it. Windows XP original version did NOT, it was added with Service Pack 1 and thereafter. Win 2000 added it with a later Service Pack - maybe SP4, but check. If your version does not have one of these Service Pack updates, download and install it BEFORE doing the cloning. Otherwise you cannot create a Partition on the HDD larger than 130 GB.