You're going to have to make a choice then, because Microsoft removed the PAE option that was in older versions of Windows.
There is no 16-bit support in 64-bit Windows, so that right there may be a deal breaker for you, and you cannot use 32-bit drivers on a 64-bit OS. So that may be another nail in the coffin.
One thing you can try, is installing a copy of a 32-bit version of Windows inside of a VM like VirtualBox. That may let you sort of split the difference, at the expense of some considerable additional overhead. You will need a second license for Windows to install into the VM, you cannot simply use the same disc and key for your current setup. If you wanted to upgrade to Windows 7 Professional or Ultimate, then you could use the XP Mode to neatly solve the problem of needing a VM and second Windows license.