Solution
You'd need a RAID controller that supports USB drives - that may be a tricky thing to find. Alternatively you could go for pure software RAID.

But USB flash drive transfer rates are abysmal, you'd have to put quite a few of them into a RAID set just to equal the transfer rate of a mechanical drive, let alone an SSD. Random I/O performance would be better, though.
You'd need a RAID controller that supports USB drives - that may be a tricky thing to find. Alternatively you could go for pure software RAID.

But USB flash drive transfer rates are abysmal, you'd have to put quite a few of them into a RAID set just to equal the transfer rate of a mechanical drive, let alone an SSD. Random I/O performance would be better, though.
 
Solution
Dec08 PCPlus (British magazine) had an article about how to do that. But because of the way that Windows treats USB drives, they had to do it in Linux. They also described how to make a cheap (and slow :)) SSD from a CompactFlash card.