First, if your memory modules have those large tall heatsinks, then you will have a problem. Some of the large tower style cpu heatsinks kind of cover up the memory slots closest to the cpu. Luckily I had standard height memory modules with standard height heatsinks. I still had to install the memory first, then install the cpu heatsink, and finally install the motherboard inside the case.
Second, some of those large tall tower style cpu heatsinks might not fit in the case if the case is not wide enough, especially if you have a case fan mounted on the side panel. It depends on the width of the case.
The memory is fine - standard height memory models with standard height heatsink. No problem there.
The case is 7.8 inches wide according to specifications at newegg.com. The problem is going to be the duct on the panel. It's the one with the "Aspire" fan grill. It sits right over where the cpu is on a motherboard. You'll have to remove the side duct if you want to install a tower style cpu heatsink. I just took another look at the photos. I definitely looks like installation of the side air duct is optional. In the next to the last photo it shows the side duct as one of the parts that can be installed. You're in luck.