i would guess that 2 260GTX would come in just under 300 watts(about 150 per card) at full(i mean like furmarks, under average use it will be lower) load.
Now the power supply has 408Watts(34 amps) of its total able to be channeled into its 12 volt rail(I say rail because it is ONE rail with 2 virtual rails for safety.)
Your cutting it very close, and overclocking the cpu does not help your power use.
I would not recommend running 2 of those cards and a Q6600 OC'd with that psu. It will most likey work, but put a large strain on the power supply(it would vary with what you use, i have never seen a game heat and power waste like AtiTool, then i found Furmark). Its nice to be able to pull extra power out in testing, but how a psu holds up under constant use is another story.
1 card would run with power to spare.
To put it into perspective
P35 DS3L
Q6600 @ 3.0 on stock voltage(Be warned 3.6 at 1.5 takes over 100 watts more)
HD 4870 @ 790 1050mem
4 Hard drives
DVD Burner
SB Audigy
While folding SMP on 3 cores and GPU on 1 core and the video card(this is not a high load since F@H does not yet use the card fully) only takes 310 watts from the plug. So people over estimate on some things. I CAN get it over 400 from the wall. There is at least 20% on new power supplies and 30-40 on older ones from the power conversion, so systems are not as power hungry as people guess.
Quick test, all cores full load and furmark = 410 watts from the plug. still under 350 watts of actual power use.