E2180 + mobo for overclocking??

if you going for e2180 stick with p35

Most P45/P35 motherboards overclock very well.

I use a P5K-E from Asus, P35 and have an E2180 @ 3ghz 8x375 1.385 volts in bios running 24/7
I know the gigabytes are excellent overclockers also, many people with 2180 also get spectacular results with the gigabyte boards.
Not to sure about the P43 chipset, but I highly doubt your future motherboard is going to limit the overclock of such a processor. Anyways just as an example I have to bump my Vcore up to 1.5 just to get to 3.2ghz stable, most people seem to hit walls when going ~3ghz+ with the E2180. You might also want to consider aftermarket cooling if you intend to keep it at 3ghz 24/7 depending on the voltages it's stable at and if you don't always have AC during the summer.

After a bit of research I found this:
http://www.dvhardware.net/article25361.html

thinking about it, the FSB on the E2180 is capped at roughly 400mhz so I have no doubt the EP43 DS3L will do as fine of a job on a E2180, and plus PCI-E 2.0 I believe does have some benefits these days. Quality P45 boards seem to be roughly $50 more expensive, so they may not be the best value.

Finally, It seems most of the recent intel chipsets like the P35 run awfully hot, putting on a little 40mm fan with tie wraps may also be a good idea to help keep it cool. Good luck with your overclock, and sorry my post isn't really in order, I write as I think sometimes.

If your looking at the E2180 why not also look at the E2200. Higher multipliers mean less stress on the motherboard to reach the same frequency.

The E2200 is the same architecture as the E21x0 chips. Just the multiplier is 1 higher so in theory it should overclock even better.

Due to its multiplier, the E2180 will not hit a FSB wall.
No need for the E2200, it will not OC better.

The EP35 DS3L does not have voltage problems and is quite renowned for being a solid board. It does have dynamic energy saving features which you may need to turn off, but since 3.0 is not a heavy OC, you likely will not even need to do that. Leaving it on if possible is actually preferable.