Along with two say, GTX 275's, would I have to run them both on the 8X lanes? There is only one 16X lane on that board correct? If I ran one of them on the 16X lane and one on the 8X would I get decreased framerates/usage?
Meaning the first card will run at x16 and the second at x8. IMO you wont see a difference (naked eye) just cause of the fact that the second GPU will be @ x8. As far as benchmarking goes, you will take a slight hit but nothing major nor noticible to the eye....
BTW there are other boards out there that have dual x16 slots.... The LE works wonders with a single massive GPU (5870 etc..) If you have not purchased the GPU/GPU's i would recommend 5870 for that specific board....