Let me assume that the primary purpose for this build is for gaming.
Read this article, and think about where you fit among the options. It will depend on what games you will play, what resolution you will use, and how much you value good gameplay. Read this and see where you are:
http://www.guru3d.com/category/vga_charts/
For the most part, it is the vga system that determines how good a game plays. In general, a high end single card like the GTX260/4870/9800gx2 will play anything out there nicely.
In my opinion, SLI or crossfire(the combining of two vga cards) is a poor value if you can be satisfied by a single strong card.
You pay more for the motherboard, and more for a more powerful psu today. If you exercise your upgrade in the future, you will be paying for a second card that is closer to being obsolete. It is better, I think, to plan on selling your old card at upgrade time, and replace it with the next best thing.
I think I would buy a E8500 up front for $20 more, and forget about overclocking. Unless your game is cpu bound like FSX or supreme commander, you will not get a big boost out of overclocking.
C2D cpu's are not very sensitive to ram speeds. Your FPS will be perhaps 1-2% better with faster ram. Very much not worth it to me. Ram is cheap, and 4gb is a good idea. Heres why:
http://www.corsairmemory.com/_appnotes/AN804_Gaming_Performance_Analysis.pdf
I would get a 4gb kit of DDR2-800 ram in a 2x2gb configuration from a quality vendor.
The Nvidia chipset motherboards seem to have more issues than the Intel P45 motherboards. Both have their fans though. If you want SLI you need a Nvidia board, if you want crossfire, you want an Intel board. If you want neither, then either board will do.
Don't go cheap on the PSU. A good quality vendor can save you some headaches. Corsair, Seasonic, PC P&C, Antec are good. Look for a tier 2 unit or better on this list:
http://www.xtremesystems.org/forums/showthread.php?t=108088
As a simple rule, any quality psu with two pcie 6 or 6/8 pin connectors will run any single vga card out there.
Most psu's out there are really single rail units. Their output is divided into several 12v. rails to limit the amps delivered on a single rail. Some consider it a safety issue. It really is a non-issue.
A psu will have a number of cables which you plug into the motherboard and other devices. A cable may have several connectors on it. This will be the sata connectors, and the 4 pin molex conectors which are used for several things like fans. A good psu recommendation is the PC P&C silencer610 for $89.99 after rebate.
http://www.newegg.com/Product/Product.aspx?Item=N82E16817703005
It will run any single vga card made, or will power a sli configuration with two lesser cards like the 8800GTS.
The P180 is a good quiet case. You can fit two of the longest cards out there like the GTX280 or 4870X2. The number of hard drives might be reduced to 3 or 4. I don't like front doors, so I might pick the Antec 300 instead.
---good luck---