I might consider spending more on a better P45 mobo but I don't know about the X38. The OP didn't indicate that was going to Xfire so I think the higher FSB achievable on the P45 would be better and besides a better OC will more than offset the dual 16x crossfire advantage. I would agree about loosing the Zalman however.
first off iplay at 1680x1050, and i forgot to point out that i dont overclock, i've had some bad experiences with it so i just stay away from it. thats the reason for the P45. but i think the zalman would be ok for stock settings, or am i wrong??