Do you want to run SLI (two Nvidia) video cards? If so, then get the MSI Eclipse. I am running the eclips with the Core i-7 D-920 and two MSI GTX 280's in SLI mode and it runs great. The x58 Pro board will do two AMD video cards in cross fire, however, unless you are using a bigger than 21" @ 1650 x 1080 resolution monitor, a single GTX 280, or AMD 4870 both with 1 gig DDR3 V-ram will actually perform better than two cards, based on test results here on Tom's. The Nvidia 295 and AMD 4870 X2 cards will also perform well on the x56 Pro board. I have run 4 MSI motherboards the past 4 years and love them. I think they are great?!