System specs, especially motherboard, RAM and PSU?
This should be your first stop.
HOWTO: Overclock C2Q (Quads) and C2D (Duals) - Guide v1.6.1http://www.tomshardware.com/forum/240001-29-howto-overclock-quads-duals-guide
Next stop should be a guide for your particular motherboard. Google is your friend.
If you have a Gigabyte motherboard, also look at this:
Shadow's Gigabyte motherboard OC guide:http://www.tomshardware.co.uk/forum/page-245679_11_0.html
It's for an EP35-DS3L but all the Gigabyte Core2 BIOS's are similar.