Only for people doing picture editing or something that requires accuracy, set up your colourimeter and then go with that.
For other people, nah, go with whatever looks good to you, but also realize that it may look cool, but it indeed may be more cartoonish or oversaturated, etc.
It's like touching up a photo, the original may be accurate but someone's skin tone may be to pale and look better with a little photo-chopped sun-in. I think it's a matter of taste, whatever works for whomever. I go out of my way for accuracy, but that's not always what makes a movie or game look the best.