Disable both CMSS-3D settings
CMSS-3D Virtual is for those who dont have surround speakers. This option gives virtual surround over the stereo speakers. Dont use this is you have 4.1 or 5.1 speakers
CMSS-3D Surround is for those who have surround speakers but use it for playing back stereo source signal (such as a CD) Gaming audio is not stereo - it is surround sound so there is no need for CMSS-3D Surround which is an upmix.
But it is handy for listening to music - try with and without it.