that's malware. Your icons and folders aren't gone, just hidden, pull your drive, put it in an external enclosure, take it to a freinds house, go to control panel>folder options and tick "show hidden files and folders" under the "view" tab. This will allow you to see your files again. After you back up all the stuff you want, go ahead and re-install windows.
Start the PC in SafeMode with Networking. Download and install Malwarebytes, run it. Do a Full Scan, remove whatever stuff it finds, reboot, see what happens.
If you got hit with a really bad virus, you may need to do waht internetlad suggested and attach your drive to another computer to back-up your files, and format the thing and start with a fresh Windows setup.