Unless you mean that you used Ghost to make an image of your OS drive while it was in a working state. And it has to be a drive image. In that case, you
Put in a new drive to replace the dead OS drive (if this is why you are doing it)
Boot to Ghost - do you have bootable media? If not, you will need to make them on another machine
Restore the drive image to the new drive
I do this often, although I am using Norton Ghost 8.0.
It is unlawful to copy your OS to another machine this way while the first machine is still in service. You have one license.