+1 to tecmo
I like to make a folder on the other drive labeled something like "Program Files 2", and then install everything in there. That way it is easy to remember where to look for the programs, and if you also want to store pictures on that drive you don't have to hunt for the picture folder through all of the stuff that installers dump when they run. I guess installers aren't too bad now, but there is still at least one folder for each program you have.