I'm wondering why you didn't choose a X38 or X48 board for your setup. Those GPU's are very powerful and you are running them at X8 instead of the X16 they crave. You are limiting the entire setup because you are using an inexpensive board on a high end setup. I would sell your board and get a new board instead of selling your GPU's. PC Hard drives are the slowest compared to the rest of your system. This is also another reason why you are seeing the few second lag. I'm not sure if I've said this enough, but sell your board and get a new one. If you are interested in the performance increase there are many boards that would suit you much better. P45 runs GPUs in Crossfire at X8 X8, X38/X48 does X16, X16, which is much faster. Cards like you have need lots of bandwidth, as they are starved right now.