Grounding the board for normal use, or while working on it outside the case?
In normal use, the motherboard is grounded to the case by each and every one of its mounting screws as well as by several of the pins in a standard 20 or 24-pin PSU connector. So long as the PSU is plugged into a properly grounded circuit, your motherboard effectively has a path directly to the earth and to every other "grounded" object resting on or in the planet.
If you remove the motherboard from the case for service or just to admire, you want to ensure that it is protected from random static discharges. This typically involves placing the motherboard on an anti-static surface (such as the anti-static bag that it was packaged in) and by you - the technician - wearing an anti-static wriststrap such as this one http://www.newegg.com/Product/Product.aspx?Item=N82E16899339002. In other words, don't worry so much about grounding the motherboard, but
do ground the technician.