First, what "are" your multiplier settings??
[BCLK, CPU Multiplier, Memory Multiplier, UCLK, QPI]
If you are running 4.xGHz without changing at least your CPU, DRAM Bus & QPI/DRAM voltages then I'm certain you'll fail Prime95 in a matter of minutes with 80C+.
You can try the following, but it is a trial by no-post process:
CPU Voltages
LoadLine Calibration.......................Level 2
CPU Vcore..................................1.33750
QPI/VTT Voltage............................1.335
CPU PLL....................................1.860
MCH/ICH Voltrage
PCIE.......................................Auto
QPI PLL....................................1.100
IOH Core...................................1.120
ICH...