It would be pushing it....would any of the GPUs hang over the motherboard (like a x16 slot at the very bottom where a dual slot card would go over)? Cause if so, id say no. ATX come to the very bottom of the space for it touching the divider plate between the PSU
In all, its a great case but imo the area for the motherboard is EXTREMELY limited.
Also keep in mind that there is very restricted space for a large PSU and will require removing the fan