Thanks for the reply.
Well, after taking out gfx card, RAM just to get hold of the hard drive I noticed it was set to slave, so I put everything back in, plugged in the hard drive, triple checking every cable is in tight, booted up the PC and for some reason it worked.
Now I have a new problem, for me to access / open it Windows asks me to format it
(You need to format the disk in drive F: before you can use it) if I do I will loose all my backup files, photos etc.
Is there any way to access it without the need to format it?