I've heard about this. Have you checked the WoW tech support forums? Here's a link to the WoW forums where someone suggests temporarily disabling Aero under Vista (if you have Vista) just prior to starting the game:
It's a known issue, though I don't know if it's related to dual GPU's or a particular Catalyst revision. Blizzard and AMD really need to work this out together.
Mine plays LOTRO: Mines of Moria just fine, Turbine just doesn't provide Crossfire support.
Message edited by yipsl on 02-26-2009 at 01:08:30 AM
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