If I buy a 4850X2 card, can I have a 3-d game running on one monitor while having the other monitor displaying something else? Obviously this works with my current 8800GT card, but I recall it being a limitation of SLI and possibly Crossfire.
Yes you can do this. Crossfire will allow you to use 2 outputs on your video card, although you will take a performance hit. I run 2 seperate 4850's and often keep other functions going on one screen while gaming on another.