Only use SLI if you can afford to pay for an x58 chipset and an i7 CPU and DDR3 ram. 7 Series SLI motherboards are very flaky and unstable. The P45 chipset for intel LGA 775 or 790fx/gx for AMD AM2+ are much more stable and you should build based on one of those two platforms. They only support crossfire, and so if you cannot afford the high priced x58 mobo, you should build for xfire, if indeed you will ever need dual GPU's. Many people would just rather build a single GPU setup for cost efficiency and heat/power consumption. Buying two gpu's does not equal double the performance, usually only 1.5x performance at best, typically 1.3-1.4x performance of just one GPU. Dual GPU setups aren't usually necessary unless you are building an extreme gaming system to play on 1920x1200 res or larger.