Going off memory here, so you may want to confirm but...
Mac hard drives need to be in GUID format to be bootable. However, if you select the "Backup - all files" option in SuperDuper, it will make an exact copy of your original hard drive including the format.This is the how-to
I followed when I upgraded my wife's macbook HDD.
If you don't already have an enclosure, I recommend this nice little unit that I used for the HDD upgrade: Transcend TS0GSJ25S-S 2.5" Silver USB 2.0 External Enclosure
I used the enclosure to house the new hard drive while cloning, then I swapped the old and new hard drives after I was finished and now use the original mac hard drive in the enclosure as a backup and to transfer files.