If your USB ports are USB 3.0 then these are easily the fastest. However, it is more likely that they are USB 2.0 - the speed differences between 1394, eSATA and USB 2 are probably too small to notice. It depends on what other devices you intend to plug into your laptop. For example: Personally I use a lot of USB devices so I would choose the eSATA as this frees up the limited number of 1394 and USB ports for other gadgets.