can I talk you out of it? what a major PITA for any sort of troubleshooting. You'd need to redo half your work every time you change configs!
Not entirely true. If it's done right, all you need to do is disconnect what you need to troubleshoot. And you would need to that anyway. And how often do you need to change configurations? Upgrading memory and CPU - no change. Adding a CrossFire or SLI'd video card? The extra power cables are right there either way. And SATA drives are much easier to work with than IDE.
And more importantly, tucking the cables down out of the way improves air flow.
My Antec 900 case modshttp://www.tomshardware.co.uk/forum/page-264112_10_0.html