Some virus/malware infections will hide all the files and shortcuts on your computer. To make your files visible again, download Unhide
to your desktop.
Once downloaded, double-click on Unhide
and allow it to run. It will remove the hidden attribute on all files and attempt to restore Quick Launch and Start Menu items to their proper location.
Then try following the steps in this virus/malware removal guide: http://www.selectrealsecurity.com/malware-removal-guide
It contains instructions that will remove most malware infections. I hope this helps you.