Not gaming, but serious work PC - first i7 build

Do you want a side window on your case, or did you just chose that one cuz its cheap? If you don't need that side window, I would do this:
http://www.newegg.com/Product/ComboDealDetails.aspx?Ite...
That is an excellent combo on a case and PSU that costs the same amount as the PSU you are looking at, but higher quality. The Case is also a bit more modest, which might be appreciated in a professional environment.

Get a motherboard that will allow a full 12gb of ram. Having only 3 dimm slots is silly on an x58 board IMO
http://www.newegg.com/Product/Product.aspx?Item=N82E168...

You don't need even that video card, its more than you need since you can't play any games. This would be more than enough for you:
http://www.newegg.com/Product/Product.aspx?Item=N82E168...

Your other selections look good. If you want to overclock, then you will need to buy a separate CPU cooler, like this one:
http://www.newegg.com/Product/Product.aspx?Item=N82E168...
If you think you can get a really stable OC, then go for it, as you will see dramatic performance boosts from overclocking. I would say 3.6ghz is a safe bet, and you wouldn't have any issues with that. However it may not be worth the risk since this is a working PC. Up to you.

Everything else looks good to me. The PSU you picked is great, but its pricey for what it offers. I'm sure the case would be fine too, but i would go for the combo I showed you.

I'm a pc building newb, but I picked the Antec 300 for my first build (just finished it less than a week ago), and I have ot say I love that case... Lots of airflow, very cool, and the large slow(ish) spinning fans are very quiet. At first, I thought they were broken. It's a very sleek- clean, stealthy case.

Also, my build is a bit more modest than yours, core 2 duo 3ghz, 4gig ram, but I went full on w/ a 750w power supply. imo- you can't have one that too big- just too small. It's a few extra bucks for piece of mind (I had old store built pc's w/ undersized power supplies- no fun).

I don't know how they work, but logically if you ahve one that you are only runny at 50% vs on at 90%, I would imagine the one at 50% capacity would deliver cleaner power (my rationalization). Plus- if I add a hard drive, or an optical drive, etc- no worries.

I also went overkill on the cpu cooler. I had a hell of a time trying to isntall the oe intel cpu cooler, so I gave up and bought a Zalman 9500. Very quiet, and easy to install. It also helps fill tat cavernous case. Looked kind of silly- empty w/ the intel one in there.

BM

IMO, when your system is fully loaded it would be ideal to have the PSU running at 50-60% of its maximum load. Running at that load level ensures the highest efficiency of the PSU (least amount of energy lost) and much less ripple in the current, which means more stability and less chance of your hardware being damaged by energy spikes (so yes you are correct in saying "cleaner power"). It also ensures that your PSU will last a long time, PSU's will burn out if they are fully loaded for an extended period of time. If you ran your system at 30% load it would be fine too, but at that point you are kinda wasting money and can get a cheaper PSU. however if you get too low of load percentage, then PSU's tend to start losing efficiency and ripple protection becomes degraded, so a 1000W PSU is not always better than a 650W PSU.

To be honest, that EA650 PSU that comes in that combo I suggested is more than you need, your system probably wouldn't need much more than 250-300W at maximum load, but the price is just too good on it to pass up. Higher wattage PSU's have higher quality parts in them, so if you can find a higher wattage PSU for the same price (assuming its a good manufacturer like Antec or Enermax or Corsair) you should get the higher wattage PSU. $107 for an Antec 300 and Antec EA650 PSU is an AWESOME deal. Its usually more like $140 for the combo, $160 or so if you buy them individually. Newegg must have more than they need and are trying to clear them out.

xthekidx,

I've noticed that most lower model GPU's like the one you posted only have 1 DVI out. I'll eventually have to use two, so I've chosen Tomshardware's suggested cheapest card.

And I do prefer a side window on the case. It's great for seeing if my fans are working properly on the CPU, GPU, case, etc... I've used the side window on my current build many times to fix bad wiring.

http://www.newegg.com/Product/Product.aspx?Item=N82E168...

What is your budget for this build exactly?