If the system is the old dimension 5510 desktop, the answer is no. The max stick size is 128 mb; possibly rdram for the Intel 850 chipset. You could change out the motherboard and power supply possibly, depending on the case backplate and form factor, but unless you're experienced, I wouldn't try it. It would be cheaper for him to buy a barebones setup with case, motherboard, and power supply. They start at around $110 at some venders listed on pricewatch. You can go with amd or Intel; amd is cheaper and works fine. Then you could donate the memory and video card to him.