D and E drive have gone missing....

[TomGraham19]

I've lost my D&E drives. I've tried about 10 different "System Restore" points but none work. I've also tried system restore in "Safe Mode" Still no joy. Any advice please

 

[ksiemb]

I've lost my D&E drives. I've tried about 10 different "System Restore" points but none work. I've also tried system restore in "Safe Mode" Still no joy. Any advice please

What shows in disk management ?
What are your D E Drives ?