dude, thing is the drivers of both games and from nvidia itself doesnt seem to run Quad SLI properly...
in theory Quad SLI would get the best performance numbers, but the drivers dont support it properly... they do supports TWO or even THREE 285's very well, so if you're going for *real world* performance that would be the better option for the time being...
eventually in the future they will properly support TWO GTX 295's, dunno if its tomorrow, or one year, or two years, but right now that isnt the case...
theres TWO articles done sometime during 2009 on toms, they compared TWO 295'S VS THREE 285's... two different articles... go have a look, it will help...
gd luck.