Certainly works for me on Windows XP with no trouble.
Also the configuration will work if your video card has 2 dvi-i connections. You can combine these with a sub-d connector to get 2650 * 1600.
What I was told by the Vidock2 seller was that windows vista will not let me combine the use of an Intel and an ATI card. My comp. has InterCore2, and the Video card has an ATI card, so I think I will need windows 7 to do this. Let me know if I am wrong, I would prefer to stay with Vista.