By saying 30" monitor, he is referring to the common native resolution on 30" monitors, which is 2560x1600, which is roughly 2-3 times the pixel count of much smaller monitors, thus requiring a lot more video ram at comparable frame rates.
GTAIV is a poorly optimized console port that consumes system resources with a ridiculous footprint. Thus, even top end hardware configurations have a tough time running it with all the eye candy (AA/AF) turned on at high resolutions. It is also VERY CPU dependent, so it requires a lot more than just a good video card to enjoy.
It is the new crysis. Get ready for a barrage of "But will it play GTAIV" comments to come in the near future.