No. Your old motherboard has a 915 chipset; won't work with any core2 duo cpus. You'll need a different board. I have used the "boston" hp board made by msi. It will run your cpu but only has 2 ram slots. It was $59 on ebay last time I checked. If you don't feel comfortable changing out a motherboard, wait and get another new system and return or sell the cpu on craigslist.