Nice spec, although I'd use a different cooler if you're looking at significant overclocking - Thermalright Ultra 120 Rev. C, Prolimatech Mehahalems, Scythe Mugen 2, Thermolab Baram, Cogage True Spirit.
The first two will need at least 1 120mm fan.
Make sure your HDD is a Samsung Spinpoint F3 - it's quick