What CPU are you using ?? - in most cases the 2x2 (4 pin CPU) plug will work for the 2x4 (8 pin CPU MOBO connector) - the manual for the MOBO should tell you what part of the plug to place the connector in leaving the other 4 pins empty ! - THe only time this will not work is if you have a CPU that needs more power than the single 4 pin plug can provide ( ie. it may be a stretch for running a 140W AMD CPU but will be fine for the lower wattage CPU's ) - IF you are using one of the 140W CPU's you may also need to get an adapter that will make a molex connector into a second 4 pin cpu adapter ( http://www.xpcgear.com/p412volt.html
) and place both into the 8 pin connector ) - since each wire can only pull so much wattage through it which is why they added the extra 4 pins to the newer MOBO's (8-pin vs. 4 pin) to support the higher power needs of these CPU's. SO it will deppend on the CPU you are using !!