Don't know if this is a super stupid response, but I just connected my own 500gb wd passport (my first ever back up drive) and you do need to double click on the drive and then double click on WD Smartware.exe to get things rolling. Then you have a few options. I chose the one that installs their cloning software first and then it started right up with the back up with one click. If you are asking about using that or another way to back it up with different software etc., sorry for the duh-ness of my response. Just not sure if you are simply having trouble getting it to back up as it doesn't just by plugging in the usb.