I'm water cooling the CPU and 2 GPUs in a Fortress FT02, which is basically the same case with a different look. Mobo rotated by 90 deg. and all that. Can be done, and it's working well for me, but I do NOT recommend it. The interior gets very cramped, and you need to remove the HDD cage to fit in a decent-sized rad in place of the stock fans. Take a look at the pic. It's a bit outdated, the insides are a bit less messy now, but you see that things get a little complicated.
I really like the look of the case, so I decided to keep it for water cooling, but it's much easier to do in something larger, with a traditional layout. Also, depends on what you want to cool. In this case, the less the better
If it's only the CPU, then of course it'll be easy.