Yes, but you shouldn't do the RAID part.
It's current best-practice to install your OS and programs on the SSD, which gives snappier startup and application loading, and then have HDDs for large amounts of data where the access and transfer speeds are less critical. That's the "Yes" part of my answer.
The "No" part of my answer is that SSDs should not be RAIDed with the current state of software, controllers, and firmware. The current wisdom (and I have been contradicted once on this, just this week, so maybe things are changing) is that A) Using RAID breaks the use of the TRIM command, so drive performance will degrade over time, and B) The SSD manufacturers build larger drives in the same series with more memory channels, so...