Bizarre multi-monitor crashes :(

Hi,

I am running a 4890 as my main card with a 4350 for my 3rd monitor. My primary monitor has a native resolution of 1920 x 1080 x 60Mhz and my two side monitors are at 1680 x 1050 x 60 Mhz.

My CPU is Phenom II 550BE running at 3.7 Mhz on Windows 7 Enterprise Full Retail Version.

These run as trips for desktop applications flawlessly. But when I try to game on the primary monitor, as soon as the graphics start, the screen goes black then shows the weirdest thing:

125 Mhz x 140Mhz Out of Range! (Everytime it locks up, I get different numbers here - really weird).

Huh?

Sorry, but I have no idea what that means? Does this mean that the 4350 is freakin out the 4890 or the different resolution secondary monitors are freakin out the primary even though I am only gaming on the primary? Who knows, but those are some crazy resolutions there.

Thanks in advance.

P.S., The system doesnt crash to a reboot, it just locks up.