huron :
Wow...that would be a lot of RAM - you might try to look into server boards if you'll need something like that.
I agree with Maziar - we'd need more info to help advise.
i believe server boards do not come with multiple PCIe x16 slots unlike NVIDIA 680 SLI ASUS motherboards
i need at least three PCIe x16 slots and since we will be dealing with a lot of fast refreshing financial data the more RAM the better,
if i talk about the most ideal setup i think my minimum goal will be at least a max capacity to increase RAM up to 48GB as 8GB x 6 as of now.
i really do not want to waste these slots with 2GB or 4GB sticks,
the higher capacity utilization the better
even x58 desktop boards are only offering single 4GB single stick compatibility in a single slot. which gives them a max capacity of only 24 GB
and i could not find any ASUS 775 board with more than max 8GB