Can my motherboard fit a NVIDEA GeForce GTS 250?

why not? your mobo has x16 PCI-e slot needed for the card. the real question might be: will GTS250 fit into my case?
btw if you want that card just make sure your PSU powerful enough to power the card

They are not the same, but a x16 v2 card will still work in an x16 v1 slot.

Your power supply is more likely to be an issue. The newer graphics cards like the 250 need a pair of 6 pin PCIE power cables. If your PSU doesnt have those you will need to replace it also.

If you had the manufacturer and model of PSU its usually not hard to check online.

Its got 30amps on the 12V rails. If you arent massively overclocking it should be adequite. IF there is a problem it will likely be the source as power supplies deteriorate over time.
http://www.newegg.com/Product/Prod [...] 6812201004
Dont put it on the same power cable as your CD/DVD. There are also SATA power to PCIE adapters if you arent using the sata power cables.

Just a note, i have an HP micro mid tower and micro atx board inside. I was able to fit the MSI GTS 250 ocv2 into it without any mods. A snug fit, but nothing bent or modified. This is in part thanks to the single 6pin connector mounted on the top of the card instead of end.

Not sure why you folks say this card needs 2 6pins. I know the GTS250 is just a rebranded version of the 9800GTX+, but the big difference is the GTS250 needs only 1 6-pin connector, smaller chip technology and better heat efficiency.

Oh and its only 9" long instead of 10.5"

Short answer, it should fit your setup, just remember these cards take up 2 slots.