SSD Optimization Guide
Just like any other hardware change, imaging the drive isn't the best way to do it, just the easiest. Most of the time there aren't any problems doing it that way.
Note that you should keep the hard drive in the system to serve as your data drive. You will want to move the user folders (My Documents, My Music, etc) to the hard drive, and install most programs to it as well. Only your most-used programs/games should be on the SSD.