I have a 2/3y old Gigabyte GA965P motherboard. Offlate a couple of USB pendrives stopped working out of no reason. A day or two later, the USB mouse gave in. Any idea what's happening? Do I need to replace the motherboard?
Yes getting a new power supply is a good idea. Your 12 volt rail is getting 16.97 volts thats just too much.
Thats not the 12 volt reading thats -12 volt which means nothing it isnt registering his 12 volt and speedfan sucks at getting voltage. If you want try HWMonitior from www.cpuid.com that is pretty accurate and to get a real reading use a multimeter to check it directly.