For the 48xx line, 100c is a huge warning sign. I believe the meltdown temp is approx 110c, but don't quote me on that. I don't have any personal experience with OCing a 4890, but your clocks are so far beyond what I have been able to see on my 4870, that I can't really give an informed opinion, hah.
Your temps look good. Your OC is high, but if stable and artifact free, awesome. Its up to you to decide how close you want to get to melting down the card, but currently your temps are pretty confidence inspiring.